Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 6/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752192 | 1.00 | MEN1 (0.54) | MEN1KMT2ATSHRTAS1R3TAS1R1 | |
| SCHEMBL9630792 | 0.85 | BCHE (0.55) | ABCB1BCHE | |
| SCHEMBL9630796 | 0.85 | BCHE (0.55) | ABCB1BCHE | |
| SCHEMBL9752711 | 0.80 | ABCB1 (0.52) | ABCB1ADCY5NR1I2ALBPDE4D | |
| SCHEMBL9752713 | 0.80 | ABCB1 (0.52) | ABCB1ADCY5NR1I2ALBPDE4D | |
| SCHEMBL9517627 | 0.78 | KDM4E (0.57) | MEN1KMT2ATSHRTAS1R3TAS1R1 | |
| SCHEMBL9517623 | 0.78 | KDM4E (0.57) | MEN1KMT2ATSHRTAS1R3TAS1R1 | |
| SCHEMBL19325459 | 0.78 | TAS1R3 (0.56) | MEN1KMT2ATSHRTAS1R3TAS1R1 | |
| SCHEMBL6560800 | 0.78 | TAS1R3 (0.56) | MEN1KMT2ATSHRTAS1R3TAS1R1 | |
| SCHEMBL2027278 | 0.77 | TAS1R3 (0.80) | MEN1KMT2ATSHRTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001318-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-02-07 | — | — | WO | disclosed |