Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630897 | 1.00 | MAOB (0.34) | MAOBMAOATLR4PTGS1PTGS2 | |
| SCHEMBL9630903 | 1.00 | MAOB (0.34) | MAOBMAOATLR4PTGS1PTGS2 | |
| SCHEMBL8737347 | 0.91 | MAOB (0.34) | MAOBMAOAPTGS1PTGS2DRD2 | |
| SCHEMBL8737349 | 0.91 | MAOB (0.34) | MAOBMAOAPTGS1PTGS2DRD2 | |
| SCHEMBL7911280 | 0.83 | TLR4 (0.33) | TLR4PTGS1PTGS2DRD2DRD3 | |
| SCHEMBL7911274 | 0.83 | TLR4 (0.33) | TLR4PTGS1PTGS2DRD2DRD3 | |
| SCHEMBL7911272 | 0.83 | TLR4 (0.33) | TLR4PTGS1PTGS2DRD2DRD3 | |
| SCHEMBL7911283 | 0.83 | TLR4 (0.33) | TLR4PTGS1PTGS2DRD2DRD3 | |
| SCHEMBL17083203 | 0.82 | MAOB (0.38) | MAOBMAOA | |
| SCHEMBL10345136 | 0.82 | NFE2L2 (0.39) | MAOBMAOATLR4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316715-B1 | CYCLOHEXANE DERIVATIVES | Chisso Corporation (JP) | 1992-06-03 | — | — | EP | disclosed |
| US-4853152-A | Cyclohexane derivative | CHISSO CORPORATION (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0316715-A2 | Cyclohexane derivatives | Chisso Corporation (JP) | 1989-05-24 | — | — | EP | disclosed |