SCHEMBL9630969

SCHEMBL9630969

Cc1ccc(Cc2ccccc2Cc2ccc(C)cc2N)c(N)c1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 10/20 0.53
SLC6A2 P23975 6/20 0.53
SLC6A3 Q01959 6/20 0.49
TDP1 Q9NUW8 3/20 0.48
ALOX15 P16050 3/20 0.48
CYP3A4 P08684 2/20 0.48
TP53 P04637 1/20 0.48
THRB P10828 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 2/20 0.43
CYP1A2 P05177 1/20 0.43
CASP7 P55210 1/20 0.43
HIF1A Q16665 1/20 0.43
CA1 P00915 1/20 0.42
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10509183 0.94 SLC6A4 (0.47) SLC6A4SLC6A2SLC6A3TDP1ALOX15
SCHEMBL4001757 0.91 ALOX15 (0.56) SLC6A4SLC6A2SLC6A3TDP1ALOX15
SCHEMBL29617187 0.91 ALOX15 (0.56) SLC6A4SLC6A2SLC6A3TDP1ALOX15
SCHEMBL22897934 0.87 SLC6A4 (0.43) SLC6A4SLC6A2SLC6A3TDP1ALOX15
SCHEMBL29559588 0.87 SLC6A4 (0.43) SLC6A4SLC6A2SLC6A3TDP1ALOX15
SCHEMBL810597 0.84 HDAC6 (0.47) SLC6A4SLC6A2SLC6A3TDP1ALOX15
SCHEMBL11779978 0.82 SLC6A4 (0.47) SLC6A4SLC6A2SLC6A3TDP1ALOX15
SCHEMBL10562423 0.81 CYP3A4 (0.50) SLC6A4SLC6A2SLC6A3TDP1ALOX15
SCHEMBL22131430 0.79 HPRT1 (0.39) SLC6A4SLC6A2SLC6A3TDP1ALOX15
SCHEMBL5032198 0.78 ALOX15 (0.56) SLC6A4SLC6A2SLC6A3TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195402-B1 BIS(HYDROXYPHTHALIMIDE) AND PROCESS FOR PREPARING THE SAME, AND PROCESS FOR PREPARING POLYESTERIMIDE BY THE USE THEREOF NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-06-10 EP disclosed
US-4855390-A Process for preparing polyesterimide from bis(hydroxyphthalimide) NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1989-08-08 US disclosed
US-4769475-A Bis(hydroxyphthalimide) and process for preparing the same, and process for preparing polyesterimide by the use thereof NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1988-09-06 US disclosed
EP-0195402-A2 Bis(hydroxyphthalimide) and process for preparing the same, and process for preparing polyesterimide by the use thereof NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1986-09-24 EP disclosed