Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 10/20 | 0.45 |
| ▸ | CES2 | O00748 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631027 | 0.89 | CES1 (0.47) | CES1CES2LMNASRCNAAA | |
| SCHEMBL20379017 | 0.87 | CES1 (0.49) | CES1CES2LMNAGAANAAA | |
| SCHEMBL29726624 | 0.86 | CES1 (0.50) | CES1CES2LMNAGAAKDM4E | |
| SCHEMBL9632450 | 0.86 | CES1 (0.50) | CES1CES2LMNAGAAKDM4E | |
| SCHEMBL9631851 | 0.84 | CES1 (0.48) | CES1CES2LMNASRCCYP2C19 | |
| SCHEMBL3128812 | 0.83 | CES1 (0.44) | CES1CES2LMNASRCCYP2C19 | |
| SCHEMBL2159286 | 0.81 | SMN1; SMN2 (0.47) | CES1CES2LMNASRCCYP2C19 | |
| Hydrochloric Acid SCHEMBL10787989 | 0.80 | CES1 (0.41) | CES1CES2LMNASRCCYP2C19 | |
| SCHEMBL28859466 | 0.79 | CA1 (0.50) | CES1CES2LMNAMAPTTDP1 | |
| SCHEMBL10471882 | 0.78 | SRC (0.47) | CES1CES2LMNASRCCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368903-B1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE) | AlliedSignal Inc. (US) | 1992-08-26 | — | — | EP | disclosed |
| EP-0368903-A1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE). | ALLIED SIGNAL INC (US) | 1990-05-23 | — | — | EP | disclosed |
| WO-1989000171-A1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE) | ALLIED-SIGNAL INC. (US) | 1989-01-12 | — | — | WO | disclosed |
| US-4767839-A | LIQUID CRYSTAL-FROM A DIACID AND DIESTERDIAMINE | ALLIED-SIGNAL INC. (US) | 1988-08-30 | — | — | US | disclosed |