Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29726624 | 1.00 | CES1 (0.50) | CES1CES2NAAAKCNH2GAA | |
| SCHEMBL20379017 | 0.98 | CES1 (0.49) | CES1CES2NAAAKCNH2GAA | |
| SCHEMBL9631027 | 0.93 | CES1 (0.47) | CES1CES2NAAAKCNH2LMNA | |
| SCHEMBL9630992 | 0.86 | CES1 (0.45) | CES1CES2NAAAGAAKDM4E | |
| SCHEMBL15993577 | 0.84 | CES2 (0.47) | CES1CES2NAAAKCNH2GAA | |
| SCHEMBL29287232 | 0.84 | CES2 (0.47) | CES1CES2NAAAKCNH2GAA | |
| SCHEMBL11416528 | 0.83 | CES1 (0.47) | CES1CES2NAAAKCNH2GAA | |
| SCHEMBL27956887 | 0.82 | HTR7 (0.51) | CES1CES2GAAMLYCDS1PR1 | |
| SCHEMBL11782068 | 0.81 | CES1 (0.51) | CES1CES2NAAAKCNH2GAA | |
| SCHEMBL11664524 | 0.81 | CES1 (0.51) | CES1CES2NAAAKCNH2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368903-B1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE) | AlliedSignal Inc. (US) | 1992-08-26 | — | — | EP | disclosed |
| EP-0368903-A1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE). | ALLIED SIGNAL INC (US) | 1990-05-23 | — | — | EP | disclosed |
| WO-1989000171-A1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE) | ALLIED-SIGNAL INC. (US) | 1989-01-12 | — | — | WO | disclosed |
| US-4767839-A | LIQUID CRYSTAL-FROM A DIACID AND DIESTERDIAMINE | ALLIED-SIGNAL INC. (US) | 1988-08-30 | — | — | US | disclosed |