SCHEMBL9631073

SCHEMBL9631073

CCCCCCCCOc1ccc([C@H]2CC[C@H](CC)CC2)c(F)c1F.CCCCCCCCOc1ccc([C@H]2CC[C@H](CCC)CC2)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
SCN9A Q15858 1/20 0.33
PPARG P37231 1/20 0.32
PLA2G2D Q9UNK4 1/20 0.32
CYP2C9 P11712 1/20 0.32
FPR2 P25090 1/20 0.32
SMPD1 P17405 3/20 0.32
ESR1 P03372 2/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
HTR1D P28221 1/20 0.32
HTR1B P28222 1/20 0.32
S1PR5 Q9H228 2/20 0.32
S1PR1 P21453 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631120 0.96 CNR1 (0.34) CNR1CNR2SCN9APPARGPLA2G2D
SCHEMBL9631114 0.96 CNR1 (0.34) CNR1CNR2SCN9APPARGPLA2G2D
SCHEMBL9406014 0.96 CNR1 (0.35) CNR1CNR2SCN9APPARGPLA2G2D
SCHEMBL9406023 0.96 CNR1 (0.35) CNR1CNR2SCN9APPARGPLA2G2D
SCHEMBL10429704 0.96 GAA (0.33) CNR1CNR2SCN9APPARGPLA2G2D
SCHEMBL10429902 0.96 GAA (0.33) CNR1CNR2SCN9APPARGPLA2G2D
SCHEMBL9630415 0.95 CNR1 (0.35) CNR1CNR2SCN9APPARGPLA2G2D
SCHEMBL9630413 0.95 CNR1 (0.35) CNR1CNR2SCN9APPARGPLA2G2D
SCHEMBL9632439 0.95 SCN9A (0.34) CNR1CNR2SCN9APPARGPLA2G2D
SCHEMBL9632443 0.95 SCN9A (0.34) CNR1CNR2SCN9APPARGPLA2G2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364538-B1 DIFLUOROBENZOL DERIVATIVES MERCK PATENT GmbH (DE) 1992-05-06 EP disclosed