Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642223 | 0.86 | PPARG (0.44) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL9632602 | 0.85 | PPARA (0.37) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL9533463 | 0.82 | PPARG (0.42) | PPARGPPARAPPARDMEN1MAPT | |
| SCHEMBL10640274 | 0.81 | PPARA (0.36) | PPARGPPARAPPARDMEN1MAPT | |
| SCHEMBL10636147 | 0.80 | PPARA (0.40) | PPARGPPARAPPARDMEN1MAPT | |
| SCHEMBL9631399 | 0.79 | PPARA (0.36) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL7454938 | 0.79 | PPARG (0.49) | PPARGMEN1MAPTKMT2ATDP1 | |
| SCHEMBL10640311 | 0.78 | PPARA (0.40) | PPARGPPARAPPARD | |
| SCHEMBL9530977 | 0.77 | PPARG (0.41) | PPARGPPARAPPARDF2F10 | |
| SCHEMBL9531649 | 0.77 | PPARG (0.51) | PPARGMEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |