Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631815 | 0.83 | HTR2A (0.49) | HTR2AFBP1IDO1PAMNPC1 | |
| SCHEMBL9633167 | 0.81 | HTR2A (0.42) | HTR2AFBP1IDO1PAMNPC1 | |
| SCHEMBL9631441 | 0.79 | HTR2A (0.41) | HTR2AFBP1IDO1PAMNPC1 | |
| SCHEMBL9632506 | 0.79 | MAPT (0.54) | NPC1RAB9AALDH1A1MAPTGAA | |
| SCHEMBL9632571 | 0.78 | FBP1 (0.53) | FBP1NPC1RAB9AALDH1A1RELA | |
| SCHEMBL9777486 | 0.75 | IDO1 (0.58) | HTR2AIDO1PAMNPC1RAB9A | |
| SCHEMBL4863423 | 0.75 | IDO1 (0.58) | HTR2AIDO1PAMNPC1RAB9A | |
| SCHEMBL28012881 | 0.72 | FBP1 (0.59) | HTR2AFBP1IDO1PAMNPC1 | |
| SCHEMBL5563497 | 0.72 | HTR2A (0.52) | HTR2AIDO1PAMNPC1SIGMAR1 | |
| SCHEMBL5563494 | 0.72 | HTR2A (0.52) | HTR2AIDO1PAMNPC1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254221-B1 | CONTRAST ENHANCEMENT LAYER COMPOSITIONS, ALKYLNITRONES, AND USE | MicroSi, Inc. (a Delaware corporation) (US) | 1992-05-13 | — | — | EP | claimed |
| EP-0254221-A2 | Contrast enhancement layer compositions, alkylnitrones, and use | MicroSi, Inc. (a Delaware corporation) (US) | 1988-01-27 | — | — | EP | claimed |
| EP-0254221-B1 | CONTRAST ENHANCEMENT LAYER COMPOSITIONS, ALKYLNITRONES, AND USE | MicroSi, Inc. (a Delaware corporation) (US) | 1992-05-13 | — | — | EP | disclosed |
| US-5106723-A | Contrast enhancement layer compositions, alkylnitrones, and use | MICROSI, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5002993-A | Contrast enhancement layer compositions, alkylnitrones, and use | MICROSI, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0254221-A2 | Contrast enhancement layer compositions, alkylnitrones, and use | MicroSi, Inc. (a Delaware corporation) (US) | 1988-01-27 | — | — | EP | disclosed |