Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632570 | 0.97 | PPARG (0.33) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL9630408 | 0.96 | PPARG (0.32) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL9630480 | 0.95 | SCN9A (0.34) | SCN9APPARGFFAR1CYP2C9PTGES | |
| SCHEMBL9631956 | 0.94 | SCN9A (0.33) | SCN9APPARGFFAR1PTGESALOX5 | |
| SCHEMBL9632709 | 0.94 | HTR2C (0.33) | PPARGCYP2C9ALOX5APFEN1ALDH1A1 | |
| SCHEMBL9630350 | 0.93 | GAA (0.33) | SCN9APPARGFFAR1PTGESALOX5 | |
| SCHEMBL9631117 | 0.92 | PPARG (0.33) | SCN9APPARGCYP2C9HTR1DHTR1B | |
| SCHEMBL9632018 | 0.92 | PPARG (0.33) | SCN9APPARGFFAR1CNR1CNR2 | |
| SCHEMBL9630340 | 0.92 | PPARG (0.33) | SCN9APPARGCYP2C9CNR1CNR2 | |
| SCHEMBL9631940 | 0.92 | SCN9A (0.34) | SCN9APPARGFFAR1HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364538-B1 | DIFLUOROBENZOL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |