Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631496 | 0.94 | SCN9A (0.34) | CYP2C9ALOX5APFEN1ALDH1A1LMNA | |
| SCHEMBL9632570 | 0.93 | PPARG (0.33) | CYP2C9FPR2PPARG | |
| SCHEMBL9631117 | 0.93 | PPARG (0.33) | HTR2CHTR2BHTR2ACYP2C9ACACB | |
| SCHEMBL9631421 | 0.93 | CYP2C9 (0.33) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9630304 | 0.92 | PPARG (0.32) | HTR2CHTR2BHTR2AMAPTMEN1 | |
| SCHEMBL9630408 | 0.92 | PPARG (0.32) | CYP2C9FPR2PPARG | |
| SCHEMBL9631259 | 0.92 | HTR2C (0.33) | HTR2CHTR2BHTR2AACACBALOX5AP | |
| SCHEMBL9631987 | 0.92 | HTR2C (0.37) | HTR2CHTR2BHTR2ACYP2C9ALDH1A1 | |
| SCHEMBL9631990 | 0.92 | HTR2C (0.37) | HTR2CHTR2BHTR2ACYP2C9ALDH1A1 | |
| SCHEMBL9630264 | 0.91 | GAA (0.33) | HTR2CHTR2BHTR2AMAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364538-B1 | DIFLUOROBENZOL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |