Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631605 | 1.00 | MAOB (0.38) | MAOBMAOACHKAMPLCTSL | |
| SCHEMBL9630563 | 0.94 | MAOB (0.39) | MAOBMAOACHKAMPLCTSL | |
| SCHEMBL9630559 | 0.94 | MAOB (0.39) | MAOBMAOACHKAMPLCTSL | |
| SCHEMBL9632384 | 0.91 | RARB (0.40) | CHKAMPLRARB | |
| SCHEMBL9632388 | 0.91 | RARB (0.40) | CHKAMPLRARB | |
| SCHEMBL9631476 | 0.91 | MAOA (0.37) | MAOBMAOACHKAMPLCTSL | |
| SCHEMBL9631472 | 0.91 | MAOA (0.37) | MAOBMAOACHKAMPLCTSL | |
| SCHEMBL9630321 | 0.91 | CHKA (0.38) | CHKARORC | |
| SCHEMBL9630317 | 0.91 | CHKA (0.38) | CHKARORC | |
| SCHEMBL9632010 | 0.90 | RARB (0.42) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364538-B1 | DIFLUOROBENZOL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |