Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782582 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 | |
| SCHEMBL9632548 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 | |
| SCHEMBL9633571 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 | |
| SCHEMBL781571 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 | |
| SCHEMBL782029 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 | |
| SCHEMBL2059032 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 | |
| SCHEMBL780584 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 | |
| SCHEMBL9631084 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 | |
| SCHEMBL9631729 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 | |
| SCHEMBL780547 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDCES2CES1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118845-A | N-butyl, N-dodecylacetamide | WHITBY RESEARCH, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0268220-B1 | PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS | WHITBY RESEARCH, Inc. (US) | 1992-05-20 | — | — | EP | disclosed |
| US-4902676-A | PENETRATION ENHANCING AND PHYSIOLOGICALLY ACTIVE AGENTS; THROUGH THE SKIN OR MUCOSAL MEMBRANE | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0329669-A4 | COMPOSITIONS COMPRISING N,N-DIALKYLALKANAMIDES AND THEIR USES. | NELSON RES & DEV COMPANY (US) | 1989-12-12 | — | — | EP | disclosed |
| EP-0329669-A1 | COMPOSITIONS COMPRISING N,N-DIALKYLALKANAMIDES AND THEIR USES | Whitby Research Incorporated (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4808414-A | DRUG DELIVERY BY SKIN ABSORPTION | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0268220-A2 | Penetration enhancers for transdermal delivery of systemic agents | WHITBY RESEARCH, Inc. (US) | 1988-05-25 | — | — | EP | disclosed |
| WO-1988002216-A1 | COMPOSITIONS COMPRISING N,N-DIALKYLALKANAMIDES AND THEIR USES | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1988-04-07 | — | — | WO | disclosed |