Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.56 |
| ▸ | PPARA | Q07869 | 12/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438045 | 0.84 | SRR (0.59) | PPARGPPARAACE | |
| SCHEMBL6438277 | 0.84 | SRR (0.59) | PPARGPPARAACE | |
| SCHEMBL15446199 | 0.80 | SRR (0.68) | PPARGPPARAHTR2AHTR2CHTR2B | |
| SCHEMBL15446174 | 0.80 | SRR (0.68) | PPARGPPARAHTR2AHTR2CHTR2B | |
| SCHEMBL6063623 | 0.78 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL26357303 | 0.78 | SLC1A3 (0.62) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6795555 | 0.77 | HTR2A (0.46) | PPARGPPARAMMP1MMP9MMP13 | |
| SCHEMBL26357253 | 0.77 | PPARG (0.58) | PPARGPPARASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14498314 | 0.76 | POLB (0.48) | PPARGPPARA | |
| SCHEMBL22767763 | 0.76 | PPARG (0.57) | PPARGPPARASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487667-A1 | PROCESS FOR PRODUCING ENANTIOMER-PURE $g(a)-HYDROXYLPROPONIOALDEHYDE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-06-03 | — | — | EP | disclosed |
| WO-1992000275-A1 | PROCESS FOR PRODUCING ENANTIOMER-PURE α-HYDROXYLPROPONIOALDEHYDE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1992-01-09 | — | — | WO | disclosed |