Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetrimonium SCHEMBL4368040 | 1.00 | DNM1 (0.58) | DNM1APAF1HSP90AA1RAD52CA1 | |
| L-Lactic Acid SCHEMBL5570547 | 1.00 | DNM1 (0.58) | DNM1APAF1HSP90AA1RAD52CA1 | |
| L-Lactic Acid SCHEMBL5573509 | 1.00 | DNM1 (0.58) | DNM1APAF1HSP90AA1RAD52CA1 | |
| L-Lactic Acid SCHEMBL5574391 | 1.00 | DNM1 (0.58) | DNM1APAF1HSP90AA1RAD52CA1 | |
| L-Lactic Acid SCHEMBL5570478 | 1.00 | DNM1 (0.58) | DNM1APAF1HSP90AA1RAD52CA1 | |
| L-Lactic Acid SCHEMBL28936548 | 1.00 | DNM1 (0.58) | DNM1APAF1HSP90AA1RAD52CA1 | |
| L-Lactic Acid SCHEMBL5574297 | 1.00 | DNM1 (0.58) | DNM1APAF1HSP90AA1RAD52CA1 | |
| L-Lactic Acid SCHEMBL5574293 | 0.98 | DNM1 (0.54) | DNM1APAF1HSP90AA1RAD52CA1 | |
| L-Lactic Acid SCHEMBL5574373 | 0.92 | CA1 (0.45) | DNM1APAF1HSP90AA1RAD52CA1 | |
| SCHEMBL5574332 | 0.90 | DNM1 (0.60) | DNM1APAF1HSP90AA1RAD52CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091350-A | Extracting with aqueous solution of organic phosphine sulfonate or carboxylate and solubilizer | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| EP-0156253-B1 | PROCESS FOR RECOVERING RHODIUM FROM OXO SYNTHESIS REACTION PRODUCTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-08 | — | — | EP | disclosed |
| US-4731485-A | Process for hydroformylation with rhodium catalysts and the separation of rhodium therefrom | RUHRCHEMIE AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | disclosed |
| EP-0156253-A2 | Process for recovering rhodium from oxo synthesis reaction products | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-02 | — | — | EP | disclosed |