SCHEMBL9632275

SCHEMBL9632275

NNC(=O)Nc1cc(F)cc(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
RAB9A P51151 2/20 0.50
GRM4 Q14833 1/20 0.49
MAPT P10636 3/20 0.47
NPSR1 Q6W5P4 1/20 0.47
IDO1 P14902 1/20 0.46
P2RY1 P47900 1/20 0.45
P2RX1 P51575 1/20 0.43
P2RX4 Q99571 1/20 0.43
P2RX7 Q99572 1/20 0.43
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
HTT P42858 1/20 0.42
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556187 0.87 MEN1 (0.61) MEN1KMT2ARAB9AGRM4MAPT
SCHEMBL29555610 0.87 MEN1 (0.61) MEN1KMT2ARAB9AGRM4MAPT
SCHEMBL9630588 0.87 MEN1 (0.60) MEN1KMT2ARAB9AGRM4MAPT
SCHEMBL8153587 0.87 ALDH1A1 (0.47) MEN1KMT2ARAB9AIDO1P2RX1
SCHEMBL20560630 0.79 GRM4 (0.53) MEN1KMT2ARAB9AGRM4MAPT
SCHEMBL3800771 0.79 GRM4 (0.56) MEN1KMT2ARAB9AGRM4MAPT
SCHEMBL29556382 0.79 MEN1 (0.51) MEN1KMT2ARAB9AGRM4MAPT
SCHEMBL29556221 0.79 MEN1 (0.51) MEN1KMT2ARAB9AGRM4MAPT
SCHEMBL29556404 0.79 MEN1 (0.51) MEN1KMT2ARAB9AGRM4MAPT
SCHEMBL29556389 0.79 MEN1 (0.51) MEN1KMT2ARAB9AGRM4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098466-A Herbicides SANDOZ LTD. (CH) 1992-03-24 US disclosed