Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631769 | 0.91 | PKM (0.42) | GLAKDM4ESMN1; SMN2MAPTTP53 | |
| SCHEMBL9632583 | 0.87 | GLA (0.41) | GLAKDM4ESMN1; SMN2MAPTTP53 | |
| SCHEMBL10364612 | 0.83 | MAPT (0.56) | GLASMN1; SMN2MAPTTP53POLB | |
| SCHEMBL9631728 | 0.83 | APEX1 (0.37) | GLAKDM4ESMN1; SMN2MAPTTP53 | |
| SCHEMBL10364759 | 0.82 | HTT (0.55) | GLAKDM4ESMN1; SMN2MAPTTP53 | |
| SCHEMBL10363894 | 0.82 | MAPT (0.60) | GLAKDM4ESMN1; SMN2MAPTTP53 | |
| SCHEMBL10435183 | 0.80 | GLA (0.37) | GLAKDM4ESMN1; SMN2MAPTTP53 | |
| SCHEMBL10435187 | 0.80 | GLA (0.37) | GLAKDM4ESMN1; SMN2MAPTTP53 | |
| SCHEMBL9633107 | 0.79 | GLA (0.34) | GLAKDM4ESMN1; SMN2MAPTTP53 | |
| SCHEMBL10364618 | 0.78 | MAPT (0.53) | SMN1; SMN2MAPTTP53THRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364396-A1 | Neumaticides and fungicides | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | claimed |
| US-5162349-A | Mercaptobis/1,3,4-oxa- and -thiadiazoles/ | CIBA-GEIGY CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0364396-A1 | Neumaticides and fungicides | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | disclosed |