Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.45 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970600 | 0.92 | MEN1 (0.61) | FAAHMEN1KMT2AMAPK1HSP90AA1 | |
| Phosphoric Acid SCHEMBL339543 | 0.86 | MEN1 (0.54) | FAAHMEN1KMT2AMAPK1HSP90AA1 | |
| SCHEMBL28881086 | 0.85 | FAAH (0.65) | FAAHMEN1KMT2AMAPK1HSP90AA1 | |
| SCHEMBL28881091 | 0.85 | FAAH (0.65) | FAAHMEN1KMT2AMAPK1HSP90AA1 | |
| SCHEMBL2146114 | 0.82 | FAAH (0.77) | FAAHMEN1KMT2AMAPK1HSP90AA1 | |
| SCHEMBL9633446 | 0.82 | FAAH (0.53) | FAAHMEN1KMT2AMAPK1HSP90AA1 | |
| SCHEMBL115804 | 0.79 | MEN1 (0.53) | FAAHMEN1KMT2AMAPK1HSP90AA1 | |
| SCHEMBL118179 | 0.79 | MEN1 (0.53) | FAAHMEN1KMT2AMAPK1HSP90AA1 | |
| SCHEMBL118547 | 0.79 | MEN1 (0.53) | FAAHMEN1KMT2AMAPK1HSP90AA1 | |
| SCHEMBL10340435 | 0.79 | FAAH (0.71) | FAAHMEN1KMT2AMAPK1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |