Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19818799 | 0.86 | L3MBTL1 (0.64) | L3MBTL1POLBLMNAGLATSHR | |
| SCHEMBL9632188 | 0.84 | L3MBTL1 (0.67) | L3MBTL1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2982115 | 0.84 | L3MBTL1 (0.67) | L3MBTL1POLBLMNAGLATSHR | |
| SCHEMBL8973343 | 0.84 | L3MBTL1 (0.67) | L3MBTL1POLBLMNAGLATSHR | |
| SCHEMBL8971899 | 0.84 | L3MBTL1 (0.67) | L3MBTL1POLBLMNAGLATSHR | |
| SCHEMBL8971856 | 0.84 | L3MBTL1 (0.67) | L3MBTL1POLBLMNAGLATSHR | |
| SCHEMBL7908984 | 0.84 | L3MBTL1 (0.67) | L3MBTL1POLBLMNAGLATSHR | |
| SCHEMBL8972793 | 0.84 | L3MBTL1 (0.67) | L3MBTL1POLBLMNAGLATSHR | |
| SCHEMBL8973067 | 0.84 | L3MBTL1 (0.67) | L3MBTL1POLBLMNAGLATSHR | |
| SCHEMBL8972353 | 0.84 | L3MBTL1 (0.67) | L3MBTL1POLBLMNAGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |