Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10491669 | 0.85 | AKR1C3 (0.42) | LTA4HSLC6A2PTGS1ADRB2ADRB1 | |
| SCHEMBL9723746 | 0.82 | NR5A1 (0.65) | LTA4HSLC6A2PTGS1NR5A1CYP1A2 | |
| SCHEMBL5702052 | 0.81 | NPC1 (0.43) | NQO1LMNAPPARA | |
| SCHEMBL12261462 | 0.81 | MAPT (0.47) | NQO1MEN1KMT2APPARA | |
| SCHEMBL12269248 | 0.81 | LMNA (0.57) | LTA4HSLC6A2PTGS1ADRB3ADRB2 | |
| SCHEMBL27037694 | 0.81 | PTGS1 (0.53) | LTA4HSLC6A2PTGS1NR5A1ADRB3 | |
| SCHEMBL27037634 | 0.81 | PTGS1 (0.53) | LTA4HSLC6A2PTGS1NR5A1ADRB3 | |
| SCHEMBL2473518 | 0.81 | SLC6A2 (0.53) | LTA4HSLC6A2PTGS1NR5A1ADRB3 | |
| SCHEMBL27132084 | 0.81 | PTGS1 (0.53) | LTA4HSLC6A2PTGS1NR5A1ADRB3 | |
| SCHEMBL9723767 | 0.80 | NR5A1 (0.68) | LTA4HNR5A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280419-B1 | OPTICALLY ACTIVE-2-SUBSTITUTED-PROPYL ETHER AND LIQUID CRYSTAL COMPOSITION | Chisso Corporation (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5032314-A | Optically active 2-substituted-propyl ether and a liquid crystal composition | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0280419-A2 | Optically active-2-substituted-propyl ether and liquid crystal composition | Chisso Corporation (JP) | 1988-08-31 | — | — | EP | disclosed |