Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | RARA | P10276 | 2/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | TACR2 | P21452 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808843 | 1.00 | HSD17B10 (0.61) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL27839969 | 0.94 | ESR1 (0.63) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL6051278 | 0.94 | ESR1 (0.63) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL1446549 | 0.94 | ESR1 (0.63) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL8750456 | 0.94 | ESR1 (0.63) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL14546512 | 0.94 | ESR1 (0.63) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL8973387 | 0.94 | ESR1 (0.63) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL11175382 | 0.94 | ESR1 (0.63) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL1445861 | 0.92 | ESR1 (0.59) | HSD17B10RARBALDH1A1ESR1ADRA2A | |
| SCHEMBL11661972 | 0.89 | HSD17B10 (0.71) | HSD17B10TSHRRARBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280419-B1 | OPTICALLY ACTIVE-2-SUBSTITUTED-PROPYL ETHER AND LIQUID CRYSTAL COMPOSITION | Chisso Corporation (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5032314-A | Optically active 2-substituted-propyl ether and a liquid crystal composition | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |