SCHEMBL8973387

SCHEMBL8973387

CCCCCCCCCCCCc1ccc(CCl)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.63
ADRA2A P08913 2/20 0.63
ADORA3 P0DMS8 2/20 0.63
TACR2 P21452 2/20 0.63
SLC6A2 P23975 2/20 0.63
SLC6A4 P31645 2/20 0.63
SLC6A3 Q01959 2/20 0.63
ALDH1A1 P00352 2/20 0.63
HSD17B10 Q99714 2/20 0.63
KDM4E B2RXH2 1/20 0.63
LMNA P02545 1/20 0.63
SHBG P04278 1/20 0.63
TP53 P04637 1/20 0.63
CYP3A4 P08684 1/20 0.63
HSPD1 P10809 1/20 0.63
ADRB3 P13945 1/20 0.63
HTR2C P28335 1/20 0.63
HSPE1 P61604 1/20 0.63
HIF1A Q16665 1/20 0.63
TST Q16762 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6051278 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1446549 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL27839969 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL14546512 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL8750456 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL11175382 1.00 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1445861 0.98 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL9808843 0.94 HSD17B10 (0.61) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL9633741 0.94 HSD17B10 (0.61) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1006989 0.91 CA2 (0.54) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315087-A Quaternary polyaminoamides PETROLITE CORPORATION (US) 1982-02-09 US claimed
CN-107986941-A A kind of method of basic hydrolysis chain alkyl benzyl halogen synthesizing long-chain alkyl benzylalcohol 江南大学 2018-05-04 CN disclosed
CN-102134283-B Preparation method of associated modified xanthan gum UNIV CHENGDU TECHNOLOGY 2013-04-24 CN disclosed
US-8329727-B2 Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment GILEAD SCIENCES, INC. (US) 2012-12-11 US disclosed
US-8329727-B2 Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment GILEAD SCIENCES, INC. (US) 2012-12-11 US disclosed
CN-102146140-B Method for preparing temperature-resistance modified water soluble cellulose ether UNIV CHENGDU TECHNOLOGY 2012-11-21 CN disclosed
CN-102146140-A Method for preparing temperature-resistance modified water soluble cellulose ether UNIV CHENGDU TECHNOLOGY 2011-08-10 CN disclosed
CN-102134283-A Preparation method of associated modified xanthan gum UNIV CHENGDU TECHNOLOGY 2011-07-27 CN disclosed
US-7790730-B2 Imidazo[4,5-d]pyrimidines, their uses and methods of preparation GILEAD SCIENCES, INC. (US) 2010-09-07 US disclosed
US-7790730-B2 Imidazo[4,5-d]pyrimidines, their uses and methods of preparation GILEAD SCIENCES, INC. (US) 2010-09-07 US disclosed
US-4703073-A DISCOLORATION INHIBITION CIBA-GEIGY CORPORATION (US) 1987-10-27 US disclosed
US-4200466-A Light-sensitive silver halide photographic materials KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-04-29 US disclosed
US-4142865-A INCORPORATING THEREIN AN OIL SOLUBLE ALKYLATED POLYBENZYL POLYMER OR COPOLYMER S.A. TEXACO BELGIUM N.V. (BE) 1979-03-06 US disclosed
US-4064091-A Process of forming a polymeric emulsion which comprises copolymerizing in aqueous dispersion an ethylenically-unsaturated monomer containing quaternary nitrogen THE KENDALL CO. (US) 1977-12-20 US disclosed
US-4042514-A Novel lubricating compositions containing derivatives of 1,2-dithiol-3-thiones or 1,2-dithiol-3-ones OROGIL (FR) 1977-08-16 US disclosed
US-4011259-A MONOMERIC EMULSION STABILIZERS THE KENDALL COMPANY (US) 1977-03-08 US disclosed
US-4011375-A POLYOLEFINS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-03-08 US disclosed
US-3974220-A POLYOXYALKYLENE ETHERS HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed
US-3969298-A Selected lipophilic aminimides and polymers derived therefrom useful for making stable emulsions THE KENDALL COMPANY (US) 1976-07-13 US disclosed
US-3936492-A Monomeric emulsion stabilizers THE KENDALL COMPANY (US) 1976-02-03 US disclosed