Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633761 | 0.92 | GAA (0.46) | NQO2GAAKMT2AHSD17B10HPGD | |
| SCHEMBL9634206 | 0.91 | NQO2 (0.46) | NQO2 | |
| SCHEMBL9633708 | 0.90 | NQO2 (0.47) | NQO2 | |
| SCHEMBL9634970 | 0.84 | NQO2 (0.49) | NQO2GAAKMT2A | |
| SCHEMBL9633716 | 0.84 | — | — | |
| SCHEMBL9633859 | 0.83 | — | — | |
| SCHEMBL9633804 | 0.83 | NQO2 (0.48) | NQO2 | |
| SCHEMBL9635029 | 0.82 | — | — | |
| SCHEMBL9633886 | 0.81 | MAPT (0.49) | NQO2GAA | |
| SCHEMBL9633776 | 0.79 | NQO2 (0.44) | NQO2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337765-B1 | ACYLSULFONAMIDE DERIVATIVES OF ALPHA-CARBOCYCLYLTOLUIC ACIDS USED AS LEUKOTRIENE ANTAGONISTS | ICI AMERICAS INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5095038-A | Antiinflammatory, antiallergens | ICI AMERICAS INC. (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0337765-A2 | Acylsulfonamide derivatives of alpha-carbocyclyltoluic acids used as leukotriene antagonists | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |