Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634717 | 0.90 | PLA2G4A (0.51) | MTNR1AMAPK1PLA2G4A | |
| SCHEMBL9634970 | 0.90 | NQO2 (0.49) | NQO2MTNR1APLA2G4AMTNR1B | |
| SCHEMBL9633886 | 0.89 | MAPT (0.49) | NQO2MTNR1AMAPTPLAUMAPK1 | |
| SCHEMBL9633776 | 0.84 | NQO2 (0.44) | NQO2MTNR1AMAPTMTNR1B | |
| SCHEMBL9634228 | 0.84 | PLA2G4A (0.51) | NQO2MTNR1AMAPTPLAUPLA2G4A | |
| SCHEMBL9634171 | 0.83 | PLA2G4A (0.53) | PLA2G4A | |
| SCHEMBL9633803 | 0.83 | NQO2 (0.48) | NQO2 | |
| SCHEMBL9633708 | 0.81 | NQO2 (0.47) | NQO2 | |
| SCHEMBL9634320 | 0.81 | CYP1A2 (0.50) | NQO2MTNR1AMAPTMTNR1B | |
| SCHEMBL9634206 | 0.81 | NQO2 (0.46) | NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337765-B1 | ACYLSULFONAMIDE DERIVATIVES OF ALPHA-CARBOCYCLYLTOLUIC ACIDS USED AS LEUKOTRIENE ANTAGONISTS | ICI AMERICAS INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5095038-A | Antiinflammatory, antiallergens | ICI AMERICAS INC. (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0337765-A2 | Acylsulfonamide derivatives of alpha-carbocyclyltoluic acids used as leukotriene antagonists | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |