Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 9/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 9/20 | 0.52 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298381 | 0.95 | NISCH (0.49) | CHRNB4CHRNA3NISCHTSHRMAPT | |
| SCHEMBL28299798 | 0.86 | HPRT1 (0.47) | CHRNB4CHRNA3NISCHTSHRMAPT | |
| Nitric Acid SCHEMBL29203949 | 0.83 | NISCH (0.40) | CHRNB4CHRNA3NISCHTSHRMAPT | |
| SCHEMBL23658900 | 0.80 | NISCH (0.40) | CHRNB4CHRNA3NISCHTSHRMAPT | |
| SCHEMBL30812588 | 0.76 | CHRNB4 (0.57) | CHRNB4CHRNA3NISCHTSHRMAPT | |
| SCHEMBL24672520 | 0.76 | CHRNB4 (0.57) | CHRNB4CHRNA3NISCHTSHRMAPT | |
| SCHEMBL25282712 | 0.74 | CHRNB4 (0.55) | CHRNB4CHRNA3TSHRMAPTGFER | |
| SCHEMBL20508918 | 0.74 | CHRNB4 (0.55) | CHRNB4CHRNA3TSHRMAPTGFER | |
| SCHEMBL4719879 | 0.74 | NISCH (0.46) | NISCHTSHRMAPTLMNAGAA | |
| SCHEMBL31544140 | 0.73 | PIK3CD (0.47) | CHRNB4CHRNA3TSHRMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132459-A | Fungicides | SANDOZ LTD. (CH) | 1992-07-21 | — | — | US | disclosed |
| US-4755534-A | Propenylamines, pharmaceutical compositions containing them and their use as pharmaceuticals | SANDOZ LTD. (CH) | 1988-07-05 | — | — | US | disclosed |
| EP-0024587-B1 | PROPENYLAMINES, PROCESSES FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS PHARMACEUTICALS | SANDOZ AG (CH) | 1984-11-14 | — | — | EP | disclosed |
| EP-0024587-A1 | Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals | SANDOZ AG (CH) | 1981-03-11 | — | — | EP | disclosed |