Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CRAT | P43155 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carnitine SCHEMBL29106391 | 0.79 | SLC22A16 (0.61) | SLC22A16ALPLPOLBALPGMAPT | |
| Carnitine SCHEMBL29015256 | 0.77 | SLC22A16 (0.71) | SLC22A16ALPLPOLBALPGMAPT | |
| Perchlorate SCHEMBL9633990 | 0.76 | MEN1 (0.46) | SLC22A16ALPLPOLBALPGMAPT | |
| Perchlorate SCHEMBL9634002 | 0.76 | MEN1 (0.46) | SLC22A16ALPLPOLBALPGMAPT | |
| Carnitine SCHEMBL28052210 | 0.76 | SLC22A16 (0.61) | SLC22A16ALPLPOLBALPGMAPT | |
| Carnitine SCHEMBL21110685 | 0.76 | SLC22A16 (0.46) | SLC22A16MAPTNPC1ALDH1A1MEN1 | |
| Levocarnitine SCHEMBL21110684 | 0.76 | SLC22A16 (0.46) | SLC22A16MAPTNPC1ALDH1A1MEN1 | |
| Levocarnitine SCHEMBL5935735 | 0.76 | SLC22A16 (0.65) | SLC22A16ALPLPOLBALPGMAPT | |
| SCHEMBL9634318 | 0.75 | MEN1 (0.50) | SLC22A16ALPLPOLBALPGMAPT | |
| SCHEMBL2201976 | 0.75 | MEN1 (0.50) | SLC22A16ALPLPOLBALPGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446185-A1 | Alpha-amino-omega-alkylthioacylcarnitines active on the cardiovascular system and pharmaceutical compositions containing same | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 1991-09-11 | — | — | EP | claimed |
| EP-0252030-B1 | DERIVATIVES OF L-AMINO ACYL L-CARNITINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS HAVING HEPATOPROTECTING ACTIVITY CONTAINING SAME | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-06-17 | — | — | EP | disclosed |
| US-4868211-A | LIVER DISORDERS | 501 SIGMA TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1989-09-19 | — | — | US | disclosed |
| US-4812478-A | Derivatives of L-amino acyl L-carnitine, process for their preparation and pharmaceutical compositions having hepatoprotecting activity containing same | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1989-03-14 | — | — | US | disclosed |
| EP-0252030-A2 | Derivatives of L-amino acyl L-carnitine, process for their preparation and pharmaceutical compositions having hepatoprotecting activity containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |