Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL9634002 | 1.00 | MEN1 (0.46) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL9634318 | 0.95 | MEN1 (0.50) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL2201976 | 0.95 | MEN1 (0.50) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL17303194 | 0.90 | MEN1 (0.46) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL28314908 | 0.83 | LMNA (0.49) | MEN1KMT2ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL2308345 | 0.82 | KMT2A (0.43) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL8184237 | 0.80 | MEN1 (0.47) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL2995885 | 0.78 | LMNA (0.44) | MEN1KMT2ACYP1A2CYP2C19CYP2D6 | |
| Levocarnitine SCHEMBL9633996 | 0.76 | SLC22A16 (0.53) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL9574228 | 0.76 | LMNA (0.42) | MEN1KMT2ACYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446185-A1 | Alpha-amino-omega-alkylthioacylcarnitines active on the cardiovascular system and pharmaceutical compositions containing same | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 1991-09-11 | — | — | EP | claimed |
| EP-0252030-B1 | DERIVATIVES OF L-AMINO ACYL L-CARNITINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS HAVING HEPATOPROTECTING ACTIVITY CONTAINING SAME | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-06-17 | — | — | EP | disclosed |
| US-5061725-A | COGNITION ACTIVATORS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1991-10-29 | — | — | US | disclosed |
| EP-0446185-A1 | Alpha-amino-omega-alkylthioacylcarnitines active on the cardiovascular system and pharmaceutical compositions containing same | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 1991-09-11 | — | — | EP | disclosed |
| US-4868211-A | LIVER DISORDERS | 501 SIGMA TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1989-09-19 | — | — | US | disclosed |
| US-4812478-A | Derivatives of L-amino acyl L-carnitine, process for their preparation and pharmaceutical compositions having hepatoprotecting activity containing same | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1989-03-14 | — | — | US | disclosed |
| EP-0252030-A2 | Derivatives of L-amino acyl L-carnitine, process for their preparation and pharmaceutical compositions having hepatoprotecting activity containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |