Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10667643 | 0.83 | CA2 (0.51) | CA2MAOBMAOAPSMB5PSMB8 | |
| SCHEMBL1252407 | 0.79 | CA2 (0.59) | CA2MAOBMAOAPSMB5PSMB8 | |
| SCHEMBL4068784 | 0.79 | IFNAR1 (0.60) | CA2MAOBMAOAIFNAR1 | |
| SCHEMBL24106036 | 0.78 | CA2 (0.58) | CA2MAOBMAOAPSMB5PSMB8 | |
| Hydrochloric Acid SCHEMBL4067559 | 0.78 | IFNAR1 (0.58) | CA2MAOBMAOAIFNAR1 | |
| SCHEMBL27776938 | 0.78 | CA2 (0.57) | CA2MAOBMAOAPSMB5PSMB8 | |
| SCHEMBL6511946 | 0.77 | MAOB (0.71) | CA2MAOBPSMB5PSMB8KDM4C | |
| SCHEMBL25029940 | 0.77 | PSMB5 (0.51) | CA2MAOBPSMB5PSMB8 | |
| SCHEMBL21376276 | 0.77 | PSMB5 (0.58) | CA2MAOBMAOAPSMB5PSMB8 | |
| SCHEMBL25029942 | 0.77 | PSMB5 (0.51) | CA2MAOBPSMB5PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3546454-B1 | BENZOHETEROCYCLYL ALKYLAMINE COMPOUND AND USE THEREOF | UNIV EAST CHINA SCIENCE & TECH (CN) | 2023-09-27 | — | — | EP | disclosed |
| US-10829464-B2 | Benzoheterocyclic alkylamine compounds and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| US-10829464-B2 | Benzoheterocyclic alkylamine compounds and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| CN-108084125-B | Benzoheterocyclylalkylamines and their use | 华东理工大学 | 2020-08-18 | — | — | CN | disclosed |
| US-20190315703-A1 | BENZOHETEROCYCLIC ALKYLAMINE COMPOUNDS AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-10-17 | — | — | US | disclosed |
| US-20190315703-A1 | BENZOHETEROCYCLIC ALKYLAMINE COMPOUNDS AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-10-17 | — | — | US | disclosed |
| EP-3546454-A1 | BENZOHETEROCYCLYL ALKYLAMINE COMPOUND AND USE THEREOF | East China University of Science and Technology (CN) | 2019-10-02 | — | — | EP | disclosed |
| EP-3546454-A1 | BENZOHETEROCYCLYL ALKYLAMINE COMPOUND AND USE THEREOF | East China University of Science and Technology (CN) | 2019-10-02 | — | — | EP | disclosed |
| WO-2018095287-A1 | BENZOHETEROCYCLYL ALKYLAMINE COMPOUND AND USE THEREOF | 华东理工大学 | 2018-05-31 | — | — | WO | disclosed |
| US-5132459-A | Fungicides | SANDOZ LTD. (CH) | 1992-07-21 | — | — | US | disclosed |
| US-4755534-A | Propenylamines, pharmaceutical compositions containing them and their use as pharmaceuticals | SANDOZ LTD. (CH) | 1988-07-05 | — | — | US | disclosed |
| EP-0024587-A1 | Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals | SANDOZ AG (CH) | 1981-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829464-B2 | Benzoheterocyclic alkylamine compounds and use thereof | AADAC, AAAS, NISCH | CA2 4489/4885MAOB 370/4885MAOA 307/4885 |
| US-20190315703-A1 | BENZOHETEROCYCLIC ALKYLAMINE COMPOUNDS AND USE THEREOF | AADAC, AAAS, NISCH | CA2 4489/4885MAOB 370/4885MAOA 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.