Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 15/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634310 | 1.00 | PLA2G4A (0.40) | PLA2G4ALTB4RCYP2C9HIF1ARARA | |
| SCHEMBL9634315 | 1.00 | PLA2G4A (0.40) | PLA2G4ALTB4RCYP2C9HIF1ARARA | |
| SCHEMBL9634720 | 0.92 | NQO2 (0.38) | MEN1NPC1RAB9AKMT2AAKR1C3 | |
| SCHEMBL9634723 | 0.92 | NQO2 (0.38) | MEN1NPC1RAB9AKMT2AAKR1C3 | |
| SCHEMBL9634713 | 0.92 | NQO2 (0.38) | MEN1NPC1RAB9AKMT2AAKR1C3 | |
| SCHEMBL9374404 | 0.82 | PLA2G4A (0.48) | PLA2G4ALTB4R | |
| SCHEMBL9374408 | 0.82 | PLA2G4A (0.48) | PLA2G4ALTB4R | |
| SCHEMBL9374394 | 0.82 | PLA2G4A (0.48) | PLA2G4ALTB4R | |
| SCHEMBL9634261 | 0.81 | NQO2 (0.41) | PLA2G4ALTB4RMEN1KMT2AAKR1C3 | |
| SCHEMBL9634254 | 0.81 | NQO2 (0.41) | PLA2G4ALTB4RMEN1KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337765-B1 | ACYLSULFONAMIDE DERIVATIVES OF ALPHA-CARBOCYCLYLTOLUIC ACIDS USED AS LEUKOTRIENE ANTAGONISTS | ICI AMERICAS INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5095038-A | Antiinflammatory, antiallergens | ICI AMERICAS INC. (US) | 1992-03-10 | — | — | US | disclosed |