Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634408 | 1.00 | KIF11 (0.49) | KIF11LMNAHIF1AKDM4EADRA2A | |
| SCHEMBL8845163 | 0.89 | KIF11 (0.49) | KIF11LMNAHIF1AKDM4EADRA2A | |
| SCHEMBL8845166 | 0.89 | KIF11 (0.49) | KIF11LMNAHIF1AKDM4EADRA2A | |
| SCHEMBL8845063 | 0.89 | KIF11 (0.49) | KIF11LMNAHIF1AKDM4EADRA2A | |
| SCHEMBL8844987 | 0.89 | KIF11 (0.49) | KIF11LMNAHIF1AKDM4EADRA2A | |
| SCHEMBL8844867 | 0.89 | KIF11 (0.49) | KIF11LMNAHIF1AKDM4EADRA2A | |
| SCHEMBL8844864 | 0.89 | KIF11 (0.49) | KIF11LMNAHIF1AKDM4EADRA2A | |
| SCHEMBL721558 | 0.86 | HCAR2 (0.51) | LMNAHIF1AKDM4EADRA2AADRA2C | |
| SCHEMBL19581639 | 0.86 | HCAR2 (0.51) | LMNAHIF1AKDM4EADRA2AADRA2C | |
| SCHEMBL19581641 | 0.86 | HCAR2 (0.51) | LMNAHIF1AKDM4EADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209363-B1 | HETEROPEPTIDES, INTERMEDIATES IN THE BIOSYNTHESIS OF PENICILLINS | Antibioticos, S.A. (ES) | 1992-05-06 | — | — | EP | disclosed |
| EP-0209363-A2 | Heteropeptides, intermediates in the biosynthesis of penicillins | Antibioticos, S.A. (ES) | 1987-01-21 | — | — | EP | disclosed |