Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421910 | 0.83 | CYP3A4 (0.38) | CYP3A4ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL14813230 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AESR1SMN1; SMN2 | |
| SCHEMBL9326850 | 0.79 | MEN1 (0.37) | CYP3A4ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29093371 | 0.75 | GAA (0.39) | ALDH1A1MEN1KMT2ATSHRALOX15 | |
| SCHEMBL27183056 | 0.72 | ALDH1A1 (0.36) | CYP3A4ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29113994 | 0.71 | TSHR (0.49) | CYP3A4ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL28109024 | 0.71 | ALDH1A1 (0.54) | ALDH1A1ESR1PKMS1PR1 | |
| SCHEMBL8423295 | 0.71 | GAA (0.42) | CYP3A4ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL1953867 | 0.70 | ALDH1A1 (0.40) | CYP3A4ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11072425 | 0.70 | NPSR1 (0.37) | CYP3A4ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287478-B1 | PROCESS FOR PREPARING AROMATIC DIAMINES CONTAINING POLYDIORGANOSILOXANE GROUPS | RHONE-POULENC CHIMIE (FR) | 1992-05-13 | — | — | EP | disclosed |
| EP-0287478-A1 | Process for preparing aromatic diamines containing polydiorganosiloxane groups | RHONE-POULENC CHIMIE (FR) | 1988-10-19 | — | — | EP | disclosed |