Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301161 | 0.98 | ROCK2 (0.44) | ROCK2CYP3A4TDP1IDO1SLC18A3 | |
| SCHEMBL54719 | 0.98 | ROCK2 (0.44) | ROCK2CYP3A4TDP1IDO1SLC18A3 | |
| SCHEMBL301129 | 0.98 | ROCK2 (0.44) | ROCK2CYP3A4TDP1IDO1SLC18A3 | |
| Phosphine SCHEMBL28231488 | 0.95 | ROCK2 (0.43) | ROCK2CYP3A4TDP1IDO1SLC18A3 | |
| SCHEMBL30727801 | 0.95 | ROCK2 (0.43) | ROCK2CYP3A4TDP1IDO1SLC18A3 | |
| SCHEMBL28530861 | 0.95 | ROCK2 (0.43) | ROCK2CYP3A4TDP1IDO1SLC18A3 | |
| SCHEMBL27521454 | 0.95 | ROCK2 (0.43) | ROCK2CYP3A4TDP1IDO1SLC18A3 | |
| SCHEMBL9516193 | 0.95 | ROCK2 (0.43) | ROCK2CYP3A4TDP1IDO1SLC18A3 | |
| Bromide SCHEMBL8849424 | 0.95 | ROCK2 (0.43) | ROCK2CYP3A4TDP1IDO1SLC18A3 | |
| SCHEMBL2271458 | 0.95 | ROCK2 (0.43) | ROCK2CYP3A4TDP1IDO1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101443302-B | Hydroformylation process with improved rhodium recovery and product separation | DOW GLOBAL TECHNOLOGIES INC | 2013-04-10 | — | — | CN | disclosed |
| CN-101778812-A | Extraction process for aldehyde product separation and catalyst recovery | DOW GLOBAL TECHNOLOGIES INC | 2010-07-14 | — | — | CN | disclosed |
| CN-101443302-A | Hydroformylation process with improved rhodium recovery and product separation | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-05-27 | — | — | CN | disclosed |
| CN-1017145-B | Hydroformylation with low volatile phosphine ligands | UNION CARBIDE CORP (US) | 1992-06-24 | — | — | CN | disclosed |
| EP-0268268-B1 | HYDROFORMYLATION USING LOW VOLATILE PHOSPHINE LIGANDS | UNION CARBIDE CORPORATION (US) | 1992-06-10 | — | — | EP | disclosed |
| CN-87101178-A | Carry out hydroformylation with low volatile phosphine ligands | — | 1988-07-06 | — | — | CN | disclosed |
| EP-0268268-A2 | Hydroformylation using low volatile phosphine ligands | UNION CARBIDE CORPORATION (US) | 1988-05-25 | — | — | EP | disclosed |
| US-4731486-A | Hydroformylation using low volatile phosphine ligands | UNION CARBIDE CORPORATION (US) | 1988-03-15 | — | — | US | disclosed |