Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.67 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146389 | 0.87 | CYP19A1 (0.52) | CYP19A1TBXAS1CYP11B2CYP11B1CYP2D6 | |
| SCHEMBL11144114 | 0.87 | CYP2D6 (0.57) | CYP19A1TBXAS1CYP11B2CYP11B1PRCP | |
| SCHEMBL11559534 | 0.82 | CYP19A1 (0.56) | CYP19A1TBXAS1CYP11B2HTR2A | |
| Eberconazole SCHEMBL353703 | 0.81 | CYP19A1 (0.46) | CYP19A1TBXAS1CYP11B2CYP11B1PRCP | |
| SCHEMBL13475616 | 0.81 | CYP19A1 (0.55) | CYP19A1TBXAS1CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL11557214 | 0.81 | CYP19A1 (0.55) | CYP19A1TBXAS1CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL9633309 | 0.80 | CYP19A1 (1.00) | CYP19A1TBXAS1CYP11B2CYP11B1CYP2D6 | |
| SCHEMBL966690 | 0.80 | CYP17A1 (0.59) | CYP19A1TBXAS1CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL10699853 | 0.78 | CYP19A1 (0.66) | CYP19A1TBXAS1CYP2D6CYP17A1TAOK1 | |
| SCHEMBL9367361 | 0.77 | CYP19A1 (0.69) | CYP19A1TBXAS1CYP11B2CYP11B1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516278-A1 | Use of anti-mullerian hormone for reversal of female sexual phenotype in poultry | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | claimed |
| EP-0514015-A1 | Control of sex differentiation in fish | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | claimed |
| US-5162337-A | Administering Steroid Biosynthesis Inhibitors | MERCK & CO., INC. (US) | 1992-11-10 | — | — | US | claimed |
| WO-1992018132-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA COMTAINING A 5 ALPHA-REDUCTASE INHIBITOR | MERCK & CO., INC. (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0479570-A2 | Animal growth promotion with aromatase inhibitors | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | claimed |
| EP-0433084-A2 | Use of aromatese inhibitors for the reversal of female sexual phenotype in poultry | MERCK & CO. INC. (US) | 1991-06-19 | — | — | EP | claimed |
| US-4757082-A | Administering imidazole or triazole derivatives | ELI LILLY AND COMPANY (US) | 1988-07-12 | — | — | US | claimed |
| EP-0516278-A1 | Use of anti-mullerian hormone for reversal of female sexual phenotype in poultry | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0514015-A1 | Control of sex differentiation in fish | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5162337-A | Administering Steroid Biosynthesis Inhibitors | MERCK & CO., INC. (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0479570-A2 | Animal growth promotion with aromatase inhibitors | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| EP-0433084-A2 | Use of aromatese inhibitors for the reversal of female sexual phenotype in poultry | MERCK & CO. INC. (US) | 1991-06-19 | — | — | EP | disclosed |