Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367361 | 0.81 | CYP19A1 (0.69) | CYP19A1CYP1A2CYP2D6CYP3A4MAPT | |
| SCHEMBL9634666 | 0.80 | CYP19A1 (0.67) | CYP19A1CYP2D6CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL3746574 | 0.74 | CYP19A1 (0.59) | CYP19A1CYP1A2CYP2D6CYP3A4MAPT | |
| SCHEMBL11559534 | 0.73 | CYP19A1 (0.56) | CYP19A1CYP11B2TBXAS1 | |
| SCHEMBL11557214 | 0.72 | CYP19A1 (0.55) | CYP19A1MAPTCYP11B1CYP11B2GAA | |
| SCHEMBL11411045 | 0.72 | CYP19A1 (0.55) | CYP19A1MAPTPOLB | |
| SCHEMBL13475616 | 0.72 | CYP19A1 (0.55) | CYP19A1CYP3A4CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL11488659 | 0.72 | CYP19A1 (0.55) | CYP19A1 | |
| SCHEMBL2822510 | 0.71 | CYP19A1 (0.54) | CYP19A1CYP3A4CYP11B2 | |
| SCHEMBL10855833 | 0.71 | CYP19A1 (0.54) | CYP19A1CYP1A2CYP2D6CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146077-B | Fluoreneimidazole derivatives and preparation method thereof | SHANGHAI UNIVERSITY (CN) | 2014-10-01 | — | — | CN | claimed |
| EP-0516278-A1 | Use of anti-mullerian hormone for reversal of female sexual phenotype in poultry | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | claimed |
| EP-0514015-A1 | Control of sex differentiation in fish | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | claimed |
| US-5162337-A | Administering Steroid Biosynthesis Inhibitors | MERCK & CO., INC. (US) | 1992-11-10 | — | — | US | claimed |
| WO-1992018132-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA COMTAINING A 5 ALPHA-REDUCTASE INHIBITOR | MERCK & CO., INC. (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0479570-A2 | Animal growth promotion with aromatase inhibitors | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | claimed |
| EP-0433084-A2 | Use of aromatese inhibitors for the reversal of female sexual phenotype in poultry | MERCK & CO. INC. (US) | 1991-06-19 | — | — | EP | claimed |
| US-4757082-A | Administering imidazole or triazole derivatives | ELI LILLY AND COMPANY (US) | 1988-07-12 | — | — | US | claimed |
| CN-105418515-A | Fluorine and imidazole derivative and preparation method thereof | UNIV SHANGHAI | 2016-03-23 | — | — | CN | disclosed |
| CN-102146077-B | Fluoreneimidazole derivatives and preparation method thereof | SHANGHAI UNIVERSITY (CN) | 2014-10-01 | — | — | CN | disclosed |
| CN-102146077-B | Fluoreneimidazole derivatives and preparation method thereof | SHANGHAI UNIVERSITY (CN) | 2014-10-01 | — | — | CN | disclosed |
| CN-102146077-B | Fluoreneimidazole derivatives and preparation method thereof | SHANGHAI UNIVERSITY (CN) | 2014-10-01 | — | — | CN | disclosed |
| CN-102267948-B | Fluoreno diimidazole derivatives and preparation method thereof | UNIV SHANGHAI | 2013-09-04 | — | — | CN | disclosed |
| CN-102146077-A | Fluoreneimidazole derivatives and preparation method thereof | UNIV SHANGHAI | 2011-08-10 | — | — | CN | disclosed |
| EP-0516278-A1 | Use of anti-mullerian hormone for reversal of female sexual phenotype in poultry | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0514015-A1 | Control of sex differentiation in fish | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5162337-A | Administering Steroid Biosynthesis Inhibitors | MERCK & CO., INC. (US) | 1992-11-10 | — | — | US | disclosed |
| WO-1992018132-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA COMTAINING A 5 ALPHA-REDUCTASE INHIBITOR | MERCK & CO., INC. (US) | 1992-10-29 | — | — | WO | disclosed |
| EP-0479570-A2 | Animal growth promotion with aromatase inhibitors | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| EP-0433084-A2 | Use of aromatese inhibitors for the reversal of female sexual phenotype in poultry | MERCK & CO. INC. (US) | 1991-06-19 | — | — | EP | disclosed |