Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2768048 | 0.78 | TDP1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28619341 | 0.78 | TDP1 (0.58) | VCAM1FASNTDP1CRHBPCRHR2 | |
| SCHEMBL30827119 | 0.78 | TDP1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| Water SCHEMBL2771683 | 0.76 | TDP1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4630194 | 0.76 | CYP2A6 (0.39) | MAPTLMNAHTTTSHRSMN1; SMN2 | |
| SCHEMBL28267591 | 0.75 | CA1 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28213415 | 0.74 | GPR35 (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9635981 | 0.74 | MAPT (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL15987733 | 0.73 | TDP1 (0.53) | FASNTDP1CRHBPCRHR2MAPT | |
| SCHEMBL30462497 | 0.73 | TDP1 (0.53) | FASNTDP1CRHBPCRHR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171852-A | Dye cellulose textiles bright reddish blue shades | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |
| EP-0279122-B1 | REACTIVE DYES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-10 | — | — | EP | disclosed |
| EP-0279122-A2 | Reactive dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | disclosed |