Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633050 | 0.95 | TSHR (0.55) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL30049181 | 0.91 | THRB (0.47) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL9634091 | 0.90 | THRB (0.54) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL9634899 | 0.87 | THRB (0.43) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL4578637 | 0.87 | THRB (0.43) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL29487385 | 0.87 | TSHR (0.49) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL1265100 | 0.87 | TSHR (0.49) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL29367471 | 0.86 | TSHR (0.51) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL30049822 | 0.86 | TSHR (0.51) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL29596732 | 0.86 | TSHR (0.51) | TSHRALDH1A1CYP3A4THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122436-A | Homogeneous blend of polyimidesiloxane and unsaturated monomer | EASTMAN KODAK COMPANY (US) | 1992-06-16 | — | — | US | disclosed |
| US-5098814-A | Integrated circuit chips of laminates of flexible metal strips and photoresists of polyimidesiloxane copolymers | EASTMAN KODAK COMPANY (US) | 1992-03-24 | — | — | US | disclosed |