Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033869 | 0.89 | CHRM5 (0.47) | CHRM5CHRM3GNAI3GNAO1GNAI1 | |
| SCHEMBL6760028 | 0.83 | CYP1A2 (0.57) | SIGMAR1ALDH1A1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL12152422 | 0.81 | PAOX (0.55) | ALDH1A1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL1909619 | 0.81 | CYP1A2 (0.60) | MEN1KMT2AALDH1A1CYP1A2MAPK1 | |
| SCHEMBL4236957 | 0.79 | PAOX (0.56) | CHRM5CHRM3CXCR4MEN1KMT2A | |
| SCHEMBL22266267 | 0.79 | MEN1 (0.43) | CHRM5CHRM3CXCR4MEN1KMT2A | |
| SCHEMBL9925862 | 0.79 | SMN1; SMN2 (0.54) | MEN1KMT2AKDM4EALDH1A1RAB9A | |
| SCHEMBL7310808 | 0.79 | MEN1 (0.49) | CHRM5CHRM3CXCR4MEN1KMT2A | |
| SCHEMBL21443809 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL17285867 | 0.77 | POLB (0.58) | MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166509-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-13 | — | — | EP | disclosed |