Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.69 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489228 | 0.97 | P2RX7 (0.72) | P2RX7MC4RKMT2AMAPK1YAP1 | |
| SCHEMBL9489224 | 0.97 | P2RX7 (0.72) | P2RX7MC4RKMT2AMAPK1YAP1 | |
| SCHEMBL6349585 | 0.93 | P2RX7 (0.73) | P2RX7KMT2AMAPK1YAP1 | |
| SCHEMBL9484631 | 0.93 | P2RX7 (0.59) | P2RX7MC4RKMT2AMAPK1 | |
| SCHEMBL9484626 | 0.93 | P2RX7 (0.59) | P2RX7MC4RKMT2AMAPK1 | |
| SCHEMBL9483220 | 0.90 | P2RX7 (0.69) | P2RX7KMT2AYAP1 | |
| SCHEMBL9484504 | 0.90 | P2RX7 (0.62) | P2RX7MC4RKMT2AMAPK1 | |
| SCHEMBL9484498 | 0.90 | P2RX7 (0.62) | P2RX7MC4RKMT2AMAPK1 | |
| SCHEMBL16466473 | 0.85 | P2RX7 (0.63) | P2RX7KMT2AMAPK1 | |
| SCHEMBL20612380 | 0.85 | P2RX7 (0.63) | P2RX7KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |