Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 13/20 | 0.62 |
| ▸ | PRKACA | P17612 | 5/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.53 |
| ▸ | AKT2 | P31751 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.53 |
| ▸ | PRKACG | P22612 | 3/20 | 0.53 |
| ▸ | PRKACB | P22694 | 3/20 | 0.53 |
| ▸ | PRKCG | P05129 | 2/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.53 |
| ▸ | AKT1 | P31749 | 2/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | MARK3 | P27448 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635104 | 1.00 | FLT3 (0.62) | FLT3PRKACAROCK2AKT2MAPK1 | |
| Hydrochloric Acid SCHEMBL9483085 | 0.99 | FLT3 (0.62) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9483651 | 0.94 | FLT3 (0.59) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9483657 | 0.94 | FLT3 (0.59) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484853 | 0.88 | FLT3 (0.58) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484851 | 0.88 | FLT3 (0.58) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL2456459 | 0.88 | FLT3 (0.56) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL2456469 | 0.88 | FLT3 (0.56) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484329 | 0.87 | FLT3 (0.63) | FLT3PRKACAROCK2AKT2MAPK1 | |
| SCHEMBL9484331 | 0.87 | FLT3 (0.63) | FLT3PRKACAROCK2AKT2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |