Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.56 |
| ▸ | PRKACA | P17612 | 5/20 | 0.49 |
| ▸ | AKT2 | P31751 | 4/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.49 |
| ▸ | PRKACG | P22612 | 3/20 | 0.49 |
| ▸ | PRKACB | P22694 | 3/20 | 0.49 |
| ▸ | PRKCG | P05129 | 2/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 2/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456459 | 1.00 | FLT3 (0.56) | FLT3PRKACAAKT2ROCK2MAPK1 | |
| SCHEMBL9483651 | 0.90 | FLT3 (0.59) | FLT3PRKACAAKT2ROCK2MAPK1 | |
| SCHEMBL9483657 | 0.90 | FLT3 (0.59) | FLT3PRKACAAKT2ROCK2MAPK1 | |
| SCHEMBL9636456 | 0.89 | FLT3 (0.54) | FLT3PRKACAAKT2ROCK2MAPK1 | |
| SCHEMBL9636453 | 0.89 | FLT3 (0.54) | FLT3PRKACAAKT2ROCK2MAPK1 | |
| Hydrochloric Acid SCHEMBL9483443 | 0.88 | FLT3 (0.54) | FLT3PRKACAAKT2ROCK2MAPK1 | |
| SCHEMBL9635104 | 0.88 | FLT3 (0.62) | FLT3PRKACAAKT2ROCK2MAPK1 | |
| SCHEMBL9635101 | 0.88 | FLT3 (0.62) | FLT3PRKACAAKT2ROCK2MAPK1 | |
| SCHEMBL2456461 | 0.88 | FLT3 (0.58) | FLT3PRKACAAKT2ROCK2MAPK1 | |
| Hydrochloric Acid SCHEMBL9483085 | 0.87 | FLT3 (0.62) | FLT3PRKACAAKT2ROCK2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | claimed |
| WO-2011146819-A2 | METHODS AND COMPOSITIONS FOR TREATMENT NF-κB-MEDIATED AND α7 INTEGRIN-SUPPRESSED DISEASES | DMD THERAPIES, LLC (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110224128-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF MUSCULAR DYSTROPHY | WHALEN ANNE | 2011-09-15 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224128-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF MUSCULAR DYSTROPHY | PYGM, TNNC1, MYOF | FLT3 4730/4885PRKACA 1337/4885AKT2 2997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.