Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 8/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636748 | 0.86 | MAPT (0.35) | RAB9AMAPTNPC1PKMBCHE | |
| SCHEMBL9510681 | 0.75 | NPC1 (0.36) | RAB9AMAPTNPC1PKMBCHE | |
| SCHEMBL11805542 | 0.64 | — | — | |
| SCHEMBL9635250 | 0.64 | MEN1 (0.40) | RAB9AMAPTNPC1PKMBCHE | |
| SCHEMBL5672876 | 0.64 | KDM4E (0.36) | RAB9AMAPTNPC1PKMBCHE | |
| SCHEMBL9177700 | 0.63 | DYRK3 (0.33) | RAB9ASMN1; SMN2 | |
| SCHEMBL9511908 | 0.63 | BCHE (0.40) | RAB9AMAPTNPC1PKMBCHE | |
| SCHEMBL9635260 | 0.62 | MAPT (0.37) | RAB9AMAPTNPC1PKMBCHE | |
| SCHEMBL9635262 | 0.62 | MAPT (0.37) | RAB9AMAPTNPC1PKMBCHE | |
| SCHEMBL9635179 | 0.62 | BCHE (0.53) | RAB9AMAPTBCHEMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0368063-A1 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |