Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 15/20 | 0.40 |
| ▸ | ACHE | P22303 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510681 | 0.89 | NPC1 (0.36) | BCHEACHENPC1MAPTRAB9A | |
| SCHEMBL9512599 | 0.81 | RAB9A (0.40) | BCHEACHENPC1MAPTRAB9A | |
| SCHEMBL9513911 | 0.78 | NPC1 (0.40) | BCHEACHENPC1MAPTRAB9A | |
| SCHEMBL9510713 | 0.77 | MAPT (0.38) | BCHEACHENPC1MAPTRAB9A | |
| SCHEMBL9513950 | 0.77 | BCHE (0.57) | BCHEACHENPC1MAPTRAB9A | |
| SCHEMBL6820707 | 0.68 | DRD3 (0.36) | ACHEMAPTPKMALDH1A1HPGD | |
| SCHEMBL9510450 | 0.66 | OPRK1 (0.41) | NPC1MAPTRAB9APKMKDM4E | |
| SCHEMBL9636748 | 0.65 | MAPT (0.35) | BCHEACHENPC1MAPTRAB9A | |
| SCHEMBL9513943 | 0.64 | MAPT (0.40) | BCHEACHENPC1MAPTRAB9A | |
| SCHEMBL9635227 | 0.63 | RAB9A (0.33) | BCHEACHENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442115-B1 | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1993-11-24 | — | — | EP | disclosed |
| US-5105036-A | Friedel-Crafts catalyst and oxy-substituted cyclic amidines as cocatylsts; preferential formation of p-isomer | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0442115-A1 | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1991-08-21 | — | — | EP | disclosed |