Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.36 |
| ▸ | PARP1 | P09874 | 7/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 5/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890090 | 0.75 | KDM4E (0.54) | CDC25BKDM4EALDH1A1MEN1GAA | |
| SCHEMBL9635092 | 0.72 | RYR2 (0.52) | RYR2PARP10PARP1PARP11HSP90AA1 | |
| SCHEMBL10888875 | 0.72 | KDM4E (0.54) | CDC25BKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9635286 | 0.71 | RYR2 (0.51) | RYR2PARP10PARP1PARP11F7 | |
| SCHEMBL9635151 | 0.70 | PARP10 (0.50) | RYR2PARP10PARP1PARP11F7 | |
| SCHEMBL1238521 | 0.70 | PRKD1 (0.50) | RYR2PARP10PARP1PARP11ALDH1A1 | |
| SCHEMBL30657972 | 0.70 | PARP10 (0.54) | RYR2PARP10PARP1PARP11HSP90AA1 | |
| SCHEMBL1238947 | 0.70 | RYR2 (0.61) | RYR2PARP10PARP1ALDH1A1MEN1 | |
| SCHEMBL26942243 | 0.70 | PARP10 (0.54) | RYR2PARP10PARP1PARP11KDM4E | |
| SCHEMBL26653947 | 0.70 | PARP10 (0.54) | RYR2PARP10PARP1PARP11HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0368063-A1 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |