Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.50 |
| ▸ | VHL | P40337 | 1/20 | 0.46 |
| ▸ | ELOC | Q15369 | 1/20 | 0.46 |
| ▸ | ELOB | Q15370 | 1/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26942243 | 0.80 | PARP10 (0.54) | PARP10PARP1RYR2PARP11GRM5 | |
| SCHEMBL26653947 | 0.80 | PARP10 (0.54) | PARP10PARP1RYR2PARP11CES1 | |
| SCHEMBL30657972 | 0.80 | PARP10 (0.54) | PARP10PARP1RYR2PARP11CES1 | |
| SCHEMBL14691900 | 0.80 | PARP10 (0.50) | PARP10PARP1RYR2PARP11GRM5 | |
| SCHEMBL1238521 | 0.80 | PRKD1 (0.50) | PARP10PARP1RYR2PARP11MEN1 | |
| SCHEMBL9636679 | 0.78 | RYR2 (0.48) | PARP10RYR2PARP11GRM5MEN1 | |
| SCHEMBL9635297 | 0.78 | PARP1 (0.55) | PARP10PARP1RYR2PARP11MEN1 | |
| SCHEMBL9032903 | 0.77 | MEN1 (0.55) | PARP10F7PARP1F3RYR2 | |
| SCHEMBL14691928 | 0.76 | RYR2 (0.78) | RYR2GRM5KDRMAP2K1METAP1 | |
| SCHEMBL5850195 | 0.75 | RYR2 (0.55) | PARP10PARP1RYR2PARP11GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |