Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.78 |
| ▸ | MPO | P05164 | 7/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726056 | 0.87 | SLC6A4 (1.00) | SLC6A4MPOHTR2ATRPM8MAPK1 | |
| SCHEMBL17367855 | 0.84 | SLC6A4 (0.72) | SLC6A4HTR2AHTR1AKMT2A | |
| SCHEMBL17367852 | 0.84 | SLC6A4 (0.82) | SLC6A4HTR2AHTR1AKMT2ABCHE | |
| SCHEMBL10953311 | 0.84 | SLC6A4 (1.00) | SLC6A4HTR2ATRPM8HTR1AGPR84 | |
| SCHEMBL8125191 | 0.82 | SLC6A4 (0.84) | SLC6A4MPOHTR2ATRPM8MAPK1 | |
| SCHEMBL10119871 | 0.81 | SLC6A4 (0.72) | SLC6A4MPOHTR2ATRPM8MAPK1 | |
| SCHEMBL10959815 | 0.81 | SLC6A4 (0.67) | SLC6A4HTR2ATRPM8HTR1AGPR84 | |
| Indalpine SCHEMBL3863561 | 0.80 | SLC6A4 (1.00) | SLC6A4MPOHTR2ABCHE | |
| Indalpine SCHEMBL29604957 | 0.80 | SLC6A4 (1.00) | SLC6A4MPOHTR2ABCHE | |
| Indalpine SCHEMBL49135 | 0.80 | SLC6A4 (1.00) | SLC6A4MPOHTR2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |