Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 10/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271475 | 0.85 | SLC6A4 (0.67) | SLC6A4GPR84HTR2ATRPM8 | |
| SCHEMBL10119820 | 0.85 | SLC6A4 (0.72) | SLC6A4GPR84HTR2ATRPM8 | |
| SCHEMBL10119730 | 0.85 | SLC6A4 (0.51) | SLC6A4FTOHTR2A | |
| SCHEMBL5726056 | 0.84 | SLC6A4 (1.00) | SLC6A4MAPK1GPR84MPOTSHR | |
| SCHEMBL10119656 | 0.82 | SLC6A4 (0.69) | SLC6A4GPR84 | |
| SCHEMBL9635299 | 0.81 | SLC6A4 (0.78) | SLC6A4MAPK1GPR84MPOHTR2A | |
| SCHEMBL1970036 | 0.80 | MPO (0.70) | SLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL8125191 | 0.79 | SLC6A4 (0.84) | SLC6A4MAPK1GPR84MPOTSHR | |
| Succinic Acid SCHEMBL6794738 | 0.78 | SLC6A4 (0.81) | SLC6A4MAPK1GPR84MPOTSHR | |
| SCHEMBL2805245 | 0.76 | GPR84 (0.59) | SLC6A4MAPK1GPR84MPOTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781639-B1 | SUBSTITUTED INDOLYL ALKYL AMINO DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-25 | — | — | EP | disclosed |