Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 1.00 |
| ▸ | MIF | P14174 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.62 |
| ▸ | TNF | P01375 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635329 | 1.00 | MAOB (1.00) | MAOBMIFMEN1ACHEKMT2A | |
| SCHEMBL979718 | 0.88 | MAOB (1.00) | MAOBMIFMEN1ACHEKMT2A | |
| SCHEMBL31179771 | 0.88 | MAOB (1.00) | MAOBMIFMEN1ACHEKMT2A | |
| SCHEMBL29595747 | 0.88 | MAOB (1.00) | MAOBMIFMEN1ACHEKMT2A | |
| SCHEMBL979717 | 0.88 | MAOB (1.00) | MAOBMIFMEN1ACHEKMT2A | |
| SCHEMBL13708801 | 0.85 | MAOB (1.00) | MAOBMIFMEN1ACHEKMT2A | |
| SCHEMBL18836413 | 0.85 | MAOB (1.00) | MAOBMIFMEN1ACHEKMT2A | |
| SCHEMBL13708805 | 0.83 | MAOB (0.71) | MAOBMIFMEN1ACHEKMT2A | |
| SCHEMBL25502260 | 0.82 | MAOB (0.72) | MAOBMIFMEN1ACHEKMT2A | |
| SCHEMBL13299560 | 0.79 | MAOB (1.00) | MAOBMIFMEN1ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |