Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.79 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26996489 | 0.91 | GPR84 (0.67) | SLC6A4GPR84MAPK1HTR2AHTR1A | |
| SCHEMBL5726056 | 0.88 | SLC6A4 (1.00) | SLC6A4GPR84MAPK1HTR2AHTR1A | |
| SCHEMBL4828133 | 0.83 | SLC6A4 (0.56) | SLC6A4GPR84MAPK1HTR2AHTR1A | |
| SCHEMBL24178671 | 0.80 | GPR84 (0.65) | SLC6A4GPR84MAPK1HTR2AHTR1A | |
| SCHEMBL8125191 | 0.80 | SLC6A4 (0.84) | SLC6A4GPR84MAPK1HTR2AHTR1A | |
| Succinic Acid SCHEMBL6794738 | 0.79 | SLC6A4 (0.81) | SLC6A4GPR84MAPK1 | |
| SCHEMBL1998835 | 0.78 | SLC6A4 (1.00) | SLC6A4GPR84 | |
| SCHEMBL26996488 | 0.78 | SLC6A4 (0.83) | SLC6A4GPR84MAPK1HTR2AHTR1A | |
| SCHEMBL30592374 | 0.78 | SLC6A4 (1.00) | SLC6A4GPR84 | |
| SCHEMBL18324757 | 0.78 | GPR84 (0.50) | SLC6A4GPR84MAPK1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |