Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704430 | 1.00 | POLB (0.50) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL2682785 | 1.00 | POLB (0.50) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL2572678 | 1.00 | POLB (0.50) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL116396 | 1.00 | POLB (0.50) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL2202494 | 1.00 | POLB (0.50) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL3041685 | 1.00 | POLB (0.50) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL7807921 | 0.89 | POLB (0.47) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL19262949 | 0.89 | CYP3A4 (0.46) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL7811172 | 0.89 | CYP1A2 (0.40) | POLBCYP1A2CYP3A4CYP2C19CHRM2 | |
| SCHEMBL117368 | 0.89 | CYP1A2 (0.40) | POLBCYP1A2CYP3A4CYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493506-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1992-07-08 | — | — | EP | disclosed |
| WO-1991004247-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1991-04-04 | — | — | WO | disclosed |