Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195052 | 0.86 | — | — | |
| SCHEMBL3389256 | 0.84 | BRD4 (0.38) | LMNABRD4BRD2 | |
| Methyl Alcohol SCHEMBL9485563 | 0.84 | BRD4 (0.43) | LMNAKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL11835015 | 0.83 | BRD4 (0.36) | LMNABRD4BRD2 | |
| Acetic Acid SCHEMBL887070 | 0.82 | BRD4 (0.39) | LMNAKDM4EMEN1CYP1A2CYP2D6 | |
| Hydrogen Peroxide SCHEMBL2561887 | 0.82 | BRD4 (0.39) | LMNAMEN1CYP1A2CYP2D6CYP2C9 | |
| Hydrogen Peroxide SCHEMBL610401 | 0.82 | BRD4 (0.39) | LMNAMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10869 | 0.82 | — | — | |
| SCHEMBL5473091 | 0.82 | BRD4 (0.42) | LMNAMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10476826 | 0.81 | BRD4 (0.35) | LMNAMEN1KMT2ABRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219207-B1 | SUSTAINED-RELEASE FORMULATION COMPRISING A HYDROPHOBIC POLYMER SYSTEM | BAUSCH & LOMB INCORPORATED (US) | 1992-07-01 | — | — | EP | disclosed |