Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636955 | 0.87 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1MAOBALOX5 | |
| SCHEMBL9635641 | 0.85 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1MAOBALOX5 | |
| SCHEMBL9635552 | 0.84 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1MAOBALOX5 | |
| SCHEMBL9757177 | 0.82 | CYSLTR1 (0.50) | CYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL9757154 | 0.75 | CYSLTR1 (0.51) | CYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL9757185 | 0.74 | CYSLTR1 (0.54) | CYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL10544491 | 0.73 | CYSLTR1 (0.66) | CYSLTR2CYSLTR1 | |
| SCHEMBL9635626 | 0.72 | KDM4E (0.56) | MAOB | |
| SCHEMBL7714576 | 0.70 | CYSLTR1 (0.64) | CYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL6088547 | 0.70 | CYSLTR1 (0.66) | CYSLTR2CYSLTR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082849-A | Antiinflammatory agents or antiallergens | AVENTIS PHARMACEUTICALS INC. | 1992-01-21 | — | — | US | disclosed |
| EP-0434827-A1 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1991001123-A2 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-02-07 | — | — | WO | disclosed |
| US-4977162-A | Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments | RORER PHARMACEUTICAL CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |